In the bone marrow are produced the leukemia cells which are abnormal and immature.These cells are clasiffied in two types:lymphoid leukemia cells and myeloid leukemia cells.The abnormal, immature cells called leukemia cells are produced by blood-forming tissue and these are named after the lymphoid or myeloid cells.
It is better to know about the normal blood cells and about the form of these.So,in the bone marrow,which is the soft material in the center of most bones, are formed the blood cells.The immature blood cells called stem cells and blasts are produced by the marrow.
These blood cells become mature,they can be formed into one of three types of mature blood cells like:red blood that carry oxygen and other materials to all tissues of the body,white blood cells that fight infection and disease,platelets that help prevent bleeding by causing blood clots to form.
One of two types of stem cells are created by mature blood cells like lymphoid stem cells or myeloid stem cells.As they grow they become lymphoid blasts, they transform in lymphocytes and then passes into white blood cells.In the same way myeloid cells grow,passes into myeloid blasts, then myelocytes and finally they become either white blood cells, red blood cells or platelets.
Abnormal cells are produced in the bone marrow and they can be either abnormal lymphoid cells or myeloid cells;appears only at people with leukemia.Lymphocytic leukemia is formed by the abnormal lymphoid cells and the myeloid leukemia is created by the abnormal myeloid cells.The types of leukemia based on the leukemia cells are four and they are the following:chronic lymphocytic leukemia (CLL),chronic myelogenous leukemia (CML),acute lymphocytic leukemia (ALL) and acute myeloid leukemia (AML).
Too many stem cells develops into either abnormal lymphoblasts or lynphocytes conduct to the appearence of lymphoid leukemia cells.Unfortunatelly lymphoblastic and lymphocytic are not abble to fight infection because of the number of lymphocytes arrises in the blood and bone marrow,there is less space for healty white blood cells,red blood cells and platelets, which can cause infection anemia and easy bleeding.
At people with leukemia there are three types of lymphocytes they became abnormal:B lymphocytes that make antibodies to help fight infection,T lymphocytes that help B lymphocytes make the antibodies that help fight infection and natural killer cells that attack cancer cells and viruses.It is important for as to know the classification of these cells and their role.
By: Groshan Fabiola