What is Acamprosate Calcium and for what Acamprosate Calcium is used?
Acamprosate Calcium medication belong to Antialcoholic agent class.
How to Take Acamprosate Calcium
Take Acamprosate Calcium exactly as prescribed by health care provider. Acamprosate Calcium is avaliable in form of Tablets, delayed-release 333 mg. acamprosate calcium (equiv. to 300 mg acamprosate).
Dosage Instructions for Acamprosate Calcium Drug
Adults: PO Two 333 mg tablets tid.
Renal Impairment Adults: PO Start with 333 mg tid in patients with moderate renal impairment (Ccr 30 to 50 mL/min). Do not administer to patients with severe renal impairment (Ccr 30 mL/min or less).
Contraindications of Acamprosate Calcium
Severe renal impairment (Ccr 30 mL/min or less); hypersensitivity to any component of product.
Interactions of Acamprosate Calcium with other drugs
Antidepressants: Weight gain and loss reported more frequently compared with either agent alone.
Naltrexone: Acamprosate levels may be increased; however, no dosage adjustment is recommended.
What are the Side Effects of Acamprosate Calcium -
Like other medicines, Acamprosate Calcium can cause side effects. Some of the more common side effects of Acamprosate Calcium includ
* Palpitation, syncope
* Insomnia (7%);
* asthenia, anxiety (6%);
* depression (5%); dizziness (3%);
* dry mouth,
* paresthesia (2%);
* headache,
* somnolence,
* decreased libido,
* amnesia,
* abnormal thinking,
* tremor,
* vasodilatation,
* hypertension (at least 1%).
* ruritus (4%);
* sweating (2%);
* rash (at least 1%).
Warnings and precautions before taking Acamprosate Calcium :
* Elderly: Because elderly are more likely to have decreased renal function, select dose of Acamprosate Calcium with care and monitor renal function.
* Reduce dose in patients with moderate renal impairment. Do not administer to patients with severe renal impairment.
* The safety and efficay of Acamprosate Calcium medicine have not been studied in children and adolescents.
* Alcohol withdrawal symptoms are not eliminated or diminished by acamprosate administration.
* Ensure that patient is participating in a comprehensive management program that includes psychosocial support.
* Monitor patient for depression or suicidal tendencies often associated with alcohol dependence. Immediately inform health care provider if depression or suicidal behaviors or thoughts are noted.
* Advise patient to continue acamprosate therapy as directed, even in the event of a relapse. Instruct patient to discuss any renewed drinking with health care provider.
* Advise women to inform health care provider if pregnant, planning to become pregnant, or breastfeeding while taking Acamprosate Calcium.
What if Overdose of Acamprosate Calcium ?
If you think you or anyone else taken overdose of Acamprosate Calcium , immediately telephone your doctor or contact your local or regional Poisons Information Centre Seek medical attention immediately. You may need urgent medical attention. Diarrhea may be a sign of overdose of Acamprosate Calcium.
What if Missed Dose of Acamprosate Calcium ?
If you miss a dose of Acamprosate Calcium medicine and you remember within an hour or so, take the dose immediately. If you do not remember until later, skip the dose you missed and go back to your regular schedule. Do not double doses.
Storage Conditions for Acamprosate Calcium :
Administer prescribed dose without regard to meals but administer with food if GI upset occurs or if administration with food increases compliance. Store Acamprosate Calcium tablets at controlled room temperature (59° to 86°F).
By: ashu